Rattus norvegicus
HDAC1
histone deacetylase 1
GO Process (46)
GO Function (23)
GO Component (15)
Gene Ontology Biological Process
- ATP-dependent chromatin remodeling [ISO]
- cellular response to oxidative stress [IDA]
- cellular response to tumor necrosis factor [IEP]
- circadian regulation of gene expression [ISO]
- circadian rhythm [ISO]
- embryonic digit morphogenesis [ISO]
- endoderm development [ISO]
- epidermal cell differentiation [ISO]
- eyelid development in camera-type eye [ISO]
- fungiform papilla formation [ISO]
- hair follicle placode formation [ISO]
- hippocampus development [ISO]
- histone H3 deacetylation [IMP, ISO]
- histone H4 deacetylation [ISO]
- histone deacetylation [ISO]
- negative regulation by host of viral transcription [ISO]
- negative regulation of I-kappaB kinase/NF-kappaB signaling [ISO]
- negative regulation of androgen receptor signaling pathway [ISO]
- negative regulation of apoptotic process [ISO]
- negative regulation of canonical Wnt signaling pathway [ISO]
- negative regulation of cell proliferation [IDA]
- negative regulation of insulin secretion [IMP]
- negative regulation of intrinsic apoptotic signaling pathway [ISO]
- negative regulation of myotube differentiation [ISO]
- negative regulation of neuron apoptotic process [IMP]
- negative regulation of peptidyl-lysine acetylation [IMP]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of transcription, DNA-templated [IDA, ISO]
- neuron differentiation [ISO]
- odontogenesis of dentin-containing tooth [ISO]
- positive regulation of cell proliferation [IMP, ISO]
- positive regulation of chemokine (C-X-C motif) ligand 2 production [IMP]
- positive regulation of interleukin-1 production [IMP]
- positive regulation of oligodendrocyte differentiation [IMP, ISO]
- positive regulation of receptor biosynthetic process [ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- positive regulation of tumor necrosis factor production [IMP]
- positive regulation of type B pancreatic cell apoptotic process [IMP]
- positive regulation of tyrosine phosphorylation of Stat3 protein [IMP]
- protein deacetylation [ISO]
- response to amphetamine [IMP]
- response to caffeine [IEP]
- response to drug [IEP]
- response to hyperoxia [IEP]
- response to lipopolysaccharide [IEP]
Gene Ontology Molecular Function- DNA binding [ISO]
- Krueppel-associated box domain binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding [ISO]
- RNA polymerase II repressing transcription factor binding [ISO]
- RNA polymerase II transcription corepressor activity [ISO]
- activating transcription factor binding [ISO]
- chromatin binding [IDA, ISO]
- core promoter binding [ISO]
- deacetylase activity [ISO]
- enzyme binding [ISO]
- histone deacetylase activity [IMP, ISO]
- histone deacetylase binding [ISO]
- nucleosomal DNA binding [ISO]
- protein binding [IPI]
- protein complex binding [IDA]
- protein deacetylase activity [ISO]
- repressing transcription factor binding [ISO]
- sequence-specific DNA binding transcription factor activity [ISO]
- transcription corepressor activity [ISO]
- transcription factor binding [IPI, ISO]
- transcription regulatory region DNA binding [ISO]
- transcription regulatory region sequence-specific DNA binding [ISO]
- DNA binding [ISO]
- Krueppel-associated box domain binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding [ISO]
- RNA polymerase II repressing transcription factor binding [ISO]
- RNA polymerase II transcription corepressor activity [ISO]
- activating transcription factor binding [ISO]
- chromatin binding [IDA, ISO]
- core promoter binding [ISO]
- deacetylase activity [ISO]
- enzyme binding [ISO]
- histone deacetylase activity [IMP, ISO]
- histone deacetylase binding [ISO]
- nucleosomal DNA binding [ISO]
- protein binding [IPI]
- protein complex binding [IDA]
- protein deacetylase activity [ISO]
- repressing transcription factor binding [ISO]
- sequence-specific DNA binding transcription factor activity [ISO]
- transcription corepressor activity [ISO]
- transcription factor binding [IPI, ISO]
- transcription regulatory region DNA binding [ISO]
- transcription regulatory region sequence-specific DNA binding [ISO]
Gene Ontology Cellular Component
- NuRD complex [ISO]
- Sin3 complex [ISO]
- chromatin [IDA, ISO]
- cytosol [ISO]
- heterochromatin [ISO]
- histone deacetylase complex [ISO]
- neuron projection [IDA]
- neuronal cell body [ISO]
- nuclear chromatin [ISO]
- nucleoplasm [ISO]
- nucleus [IDA, ISO]
- perinuclear region of cytoplasm [IDA]
- protein complex [IDA, ISO]
- transcription factor complex [ISO]
- transcriptional repressor complex [ISO]
Download Curated Data for this Protein
255695
10116
Switch View:
- Interactors 6
- Interactions 6
- Network