Rattus norvegicus
PKD2
RGD1559992
polycystic kidney disease 2 (autosomal dominant)
GO Process (52)
GO Function (20)
GO Component (21)
Gene Ontology Biological Process
- JAK-STAT cascade [ISO]
- aorta development [ISO]
- branching involved in ureteric bud morphogenesis [ISO]
- calcium ion transmembrane transport [ISO]
- calcium ion transport [ISO]
- cell cycle arrest [ISO]
- cellular calcium ion homeostasis [ISO]
- cellular response to fluid shear stress [ISO]
- cellular response to hydrostatic pressure [ISO]
- cellular response to osmotic stress [ISO]
- cytoplasmic sequestering of transcription factor [ISO]
- detection of mechanical stimulus [IBA, ISO]
- detection of nodal flow [ISO]
- determination of left/right symmetry [ISO]
- determination of liver left/right asymmetry [ISO]
- embryonic placenta development [ISO]
- heart development [ISO]
- heart looping [ISO]
- kidney development [ISO]
- liver development [ISO]
- mesonephric duct development [ISO]
- mesonephric tubule development [ISO]
- metanephric S-shaped body morphogenesis [ISO]
- metanephric ascending thin limb development [ISO]
- metanephric cortex development [ISO]
- metanephric cortical collecting duct development [ISO]
- metanephric distal tubule development [ISO]
- metanephric mesenchyme development [ISO]
- metanephric part of ureteric bud development [ISO]
- metanephric smooth muscle tissue development [ISO]
- negative regulation of G1/S transition of mitotic cell cycle [ISO]
- negative regulation of ryanodine-sensitive calcium-release channel activity [ISO]
- neural tube development [ISO]
- placenta blood vessel development [ISO]
- positive regulation of cell cycle arrest [ISO]
- positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [ISO]
- positive regulation of cytosolic calcium ion concentration [IMP]
- positive regulation of gene expression [ISO]
- positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [ISO]
- positive regulation of nitric oxide biosynthetic process [ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- potassium ion transmembrane transport [ISO]
- regulation of cAMP metabolic process [ISO]
- regulation of calcium ion import [ISO]
- regulation of cell proliferation [ISO]
- release of sequestered calcium ion into cytosol [ISO]
- renal artery morphogenesis [ISO]
- renal system development [ISO]
- renal tubule morphogenesis [ISO]
- sodium ion transmembrane transport [ISO]
- spinal cord development [ISO]
- transmembrane transport [ISO]
Gene Ontology Molecular Function- ATPase binding [ISO]
- HLH domain binding [ISO]
- actinin binding [ISO]
- alpha-actinin binding [IPI]
- calcium channel activity [IBA, ISO]
- calcium ion binding [ISO]
- calcium-induced calcium release activity [ISO]
- channel activity [ISO]
- cytoskeletal protein binding [ISO]
- identical protein binding [ISO]
- ion channel binding [ISO]
- muscle alpha-actinin binding [IPI]
- phosphoprotein binding [ISO]
- potassium channel activity [ISO]
- protein homodimerization activity [ISO]
- receptor binding [ISO]
- voltage-gated calcium channel activity [ISO]
- voltage-gated cation channel activity [ISO]
- voltage-gated ion channel activity [ISO]
- voltage-gated sodium channel activity [ISO]
- ATPase binding [ISO]
- HLH domain binding [ISO]
- actinin binding [ISO]
- alpha-actinin binding [IPI]
- calcium channel activity [IBA, ISO]
- calcium ion binding [ISO]
- calcium-induced calcium release activity [ISO]
- channel activity [ISO]
- cytoskeletal protein binding [ISO]
- identical protein binding [ISO]
- ion channel binding [ISO]
- muscle alpha-actinin binding [IPI]
- phosphoprotein binding [ISO]
- potassium channel activity [ISO]
- protein homodimerization activity [ISO]
- receptor binding [ISO]
- voltage-gated calcium channel activity [ISO]
- voltage-gated cation channel activity [ISO]
- voltage-gated ion channel activity [ISO]
- voltage-gated sodium channel activity [ISO]
Gene Ontology Cellular Component
- basal cortex [ISO]
- basal plasma membrane [ISO]
- cell-cell junction [ISO]
- ciliary basal body [ISO]
- cilium [ISO]
- cytoplasm [ISO]
- cytosol [ISO]
- endoplasmic reticulum [IDA, ISO]
- endoplasmic reticulum membrane [ISO]
- extracellular vesicular exosome [ISO]
- filamentous actin [ISO]
- integral component of cytoplasmic side of endoplasmic reticulum membrane [ISO]
- integral component of lumenal side of endoplasmic reticulum membrane [ISO]
- integral component of plasma membrane [ISO]
- lamellipodium [ISO]
- membrane [IDA]
- mitotic spindle [ISO]
- motile primary cilium [ISO]
- nonmotile primary cilium [ISO]
- plasma membrane [ISO]
- polycystin complex [ISO]
269638
10116