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Saccharomyces cerevisiae (S288c)

HCM1

L000000757, YCR065W

Forkhead transcription factor; drives S-phase specific expression of genes involved in chromosome segregation, spindle dynamics, and budding; suppressor of calmodulin mutants with specific SPB assembly defects; telomere maintenance role; regulates replicative lifespan; ortholog of C. elegans lifespan regulator PHA-4

GO Process (5)

GO Function (4)

GO Component (4)

Gene Ontology Biological Process

cellular response to oxidative stress [IMP]

mitochondrion organization [IMP]

positive regulation of transcription from RNA polymerase II promoter [IDA]

regulation of sequence-specific DNA binding transcription factor activity [IBA]

spindle pole body organization [IGI]

Gene Ontology Molecular Function

RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IBA]
double-stranded DNA binding [IBA]
sequence-specific DNA binding [IDA, IMP]
transcription factor binding [IBA]

Gene Ontology Cellular Component

cytoplasm [IDA]

nuclear chromatin [IDA]

transcription factor complex [IBA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

31041

559292

Interactors 306
Interactions 562
Network
PTM Sites 13