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Saccharomyces cerevisiae (S288c)

SED4

L000001860, YCR067C

Integral ER membrane protein that stimulates Sar1p GTPase activity; involved in COPII vesicle budding through disassociation of coat proteins from membranes onto liposomes; binds Sec16p; SED4 has a paralog, SEC12, that arose from the whole genome duplication

GO Process (2)

GO Function (1)

GO Component (2)

Gene Ontology Biological Process

positive regulation of GTPase activity [IDA, IPI]

regulation of COPII vesicle coating [IDA]

Gene Ontology Molecular Function

Sar GTPase activator activity [IDA, IPI]

Gene Ontology Cellular Component

cytoplasm [IDA]

integral component of endoplasmic reticulum membrane [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

31043

559292

Interactors 116
Interactions 158
Network
PTM Sites 4