Saccharomyces cerevisiae (S288c)
YPI1
YFR003C
Regulatory subunit of the type I protein phosphatase (PP1) Glc7p; Glc7p participates in the regulation of a variety of metabolic processes including mitosis and glycogen metabolism; in vitro evidence suggests Ypi1p is an inhibitor of Glc7p while in vivo evidence suggests it is an activator; overproduction causes decreased cellular content of glycogen; partial depletion causes lithium sensitivity, while overproduction confers lithium-tolerance
GO Process (7)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
- cellular ion homeostasis [IMP]
- glycogen metabolic process [IMP]
- mitotic spindle assembly checkpoint [IGI]
- negative regulation of phosphoprotein phosphatase activity [IDA, IMP]
- negative regulation of protein dephosphorylation [IDA, IMP]
- positive regulation of phosphoprotein phosphatase activity [IGI]
- regulation of protein localization to nucleus [IDA, IMP]
Gene Ontology Molecular Function
Download Curated Data for this Protein
31151
559292
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- Interactors 163
- Interactions 192
- Network
- PTM Sites 8