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Saccharomyces cerevisiae (S288c)

DCS1

DcpS, YLR270W

Non-essential hydrolase involved in mRNA decapping; activates Xrn1p; may function in a feedback mechanism to regulate deadenylation, contains pyrophosphatase activity and a HIT (histidine triad) motif; acts as inhibitor of neutral trehalase Nth1p; required for growth on glycerol medium; protein abundance increases in response to DNA replication stress; DCS1 has a paralog, DCS2, that arose from the whole genome duplication

GO Process (3)

GO Function (3)

GO Component (4)

Gene Ontology Biological Process

deadenylation-dependent decapping of nuclear-transcribed mRNA [IDA, IMP, ISS]

nuclear-transcribed mRNA catabolic process, deadenylation-independent decay [IGI, IMP]

positive regulation of exoribonuclease activity [IDA, IPI]

Gene Ontology Molecular Function

exoribonuclease activator activity [IDA, IPI]
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [IDA, IMP, ISS]
m7G(5')pppN diphosphatase activity [IDA]

Gene Ontology Cellular Component

cytoplasm [IDA]

cytoplasmic mRNA processing body [IDA]

mitochondrion [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

31537

559292

Interactors 95
Interactions 101
Network
PTM Sites 10