BioGRID COVID-19 Coronavirus Curation Project
Search BioGRID for SARS-CoV-2 Protein Interactions | Download SARS-CoV-2 and Coronavirus-Related Interactions

Saccharomyces cerevisiae (S288c)

ROM2

Rho family guanine nucleotide exchange factor ROM2, L000003182, YLR371W

GDP/GTP exchange factor (GEF) for Rho1p and Rho2p; mutations are synthetically lethal with mutations in rom1, which also encodes a GEF; Rom2p localization to the bud surface is dependent on Ack1p; ROM2 has a paralog, ROM1, that arose from the whole genome duplication

GO Process (6)

GO Function (3)

GO Component (3)

Gene Ontology Biological Process

activation of Rho GTPase activity [IDA]

establishment of cell polarity [IMP]

negative regulation of cAMP-mediated signaling [IGI, IMP]

positive regulation of endocytosis [IMP]

regulation of fungal-type cell wall organization [IGI]

small GTPase mediated signal transduction [IPI]

Gene Ontology Molecular Function

Rho guanyl-nucleotide exchange factor activity [IDA, IPI]
phosphatidylinositol-4,5-bisphosphate binding [IDA]
signal transducer activity [IGI]

Gene Ontology Cellular Component

cellular bud tip [IDA]

incipient cellular bud site [IDA]

mating projection tip [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

31631

559292

Interactors 814
Interactions 1,141
Network
PTM Sites 53