Saccharomyces cerevisiae (S288c)

HMG2

hydroxymethylglutaryl-CoA reductase (NADPH) HMG2, L000000790, YLR450W
HMG-CoA reductase; converts HMG-CoA to mevalonate, a rate-limiting step in sterol biosynthesis; one of two isozymes; overproduction induces assembly of peripheral ER membrane arrays and short nuclear-associated membrane stacks; forms foci at the nuclear periphery upon DNA replication stress; HMG2 has a paralog, HMG1, that arose from the whole genome duplication
UBI
PHO
GO Process (1)
GO Function (1)
GO Component (4)

External Database Linkouts

SGD | Entrez Gene | RefSeq | UniprotKB | PhosphoGRID
Download 94 Published Interactions For This Protein
31708
559292
  • Stats & Options
Switch View:
  • Interactors (64)
  • Interactions (94)
  • Network
  • PTM Sites (7)