Saccharomyces cerevisiae (S288c)

HMG2

hydroxymethylglutaryl-CoA reductase (NADPH) HMG2, L000000790, YLR450W
HMG-CoA reductase; converts HMG-CoA to mevalonate, a rate-limiting step in sterol biosynthesis; one of two isozymes; overproduction induces assembly of peripheral ER membrane arrays and short nuclear-associated membrane stacks; forms foci at the nuclear periphery upon DNA replication stress; HMG2 has a paralog, HMG1, that arose from the whole genome duplication
P
GO Process: 1 Terms
GO Function: 1 Terms
GO Component: 4 Terms

External Database Linkouts

SGD | Entrez Gene | RefSeq | UniprotKB | PhosphoGRID
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  • PTM Sites (6)