Saccharomyces cerevisiae (S288c)

CWC2

NTC40, YDL209C

Member of the NineTeen Complex (NTC); this complex contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; binds directly to U6 snRNA; similar to S. pombe Cwf2

GO Process (3)

GO Function (4)

GO Component (3)

Gene Ontology Biological Process

mRNA cis splicing, via spliceosome [IMP]

mRNA splicing, via spliceosome [IMP]

spliceosomal snRNP assembly [IDA]

Gene Ontology Molecular Function

U6 snRNA binding [IDA]
first spliceosomal transesterification activity [IC]
pre-mRNA binding [IDA]
second spliceosomal transesterification activity [IC]

Gene Ontology Cellular Component

Prp19 complex [IPI]

U2-type catalytic step 1 spliceosome [IDA]

U2-type catalytic step 2 spliceosome [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

31837

559292

Interactors 124
Interactions 251
Network
PTM Sites 5

Result Summary

CWC2

Gene Ontology Biological Process

Gene Ontology Molecular Function

U6 snRNA binding [IDA]first spliceosomal transesterification activity [IC]pre-mRNA binding [IDA]second spliceosomal transesterification activity [IC]

Gene Ontology Cellular Component

U6 snRNA binding [IDA]
first spliceosomal transesterification activity [IC]
pre-mRNA binding [IDA]
second spliceosomal transesterification activity [IC]