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Saccharomyces cerevisiae (S288c)

GLE1

BRR3, NLE2, RSS1, nucleoporin GLE1, L000003399, L000001255, S000029324, YDL207W

Cytoplasmic nucleoporin required for polyadenylated mRNA export; contains a nuclear export signal; when bound to inositol hexakisphosphate (IP6), functions as an activator for the Dbp5p ATPase activity at the nuclear pore complex during mRNA export; mediates translation initiation; required for efficient translation termination

GO Process (4)

GO Function (4)

GO Component (5)

Gene Ontology Biological Process

mRNA export from nucleus [IMP]

poly(A)+ mRNA export from nucleus [IMP]

regulation of translational initiation [IMP]

regulation of translational termination [IMP]

Gene Ontology Molecular Function

enzyme activator activity [IDA, IGI, IMP]
inositol hexakisphosphate binding [IDA]
phospholipid binding [IDA]
translation initiation factor binding [IPI]

Gene Ontology Cellular Component

cytoplasm [IDA]

integral component of membrane [ISM]

mitochondrion [IDA]

nuclear pore [IDA]

nuclear pore cytoplasmic filaments [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

31839

559292

Interactors 462
Interactions 597
Network
PTM Sites 1