Saccharomyces cerevisiae (S288c)

CDC53

cullin CDC53, L000000281, YDL132W

Cullin; structural protein of SCF complexes (which also contain Skp1p, Cdc34p, Hrt1p and an F-box protein) involved in ubiquitination; SCF promotes the G1-S transition by targeting G1 cyclins and the Cln-CDK inhibitor Sic1p for degradation

UPS Project

GO Process (4)

GO Function (4)

GO Component (1)

Gene Ontology Biological Process

G1/S transition of mitotic cell cycle [IMP]

G2/M transition of mitotic cell cycle [IGI]

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [IDA]

protein ubiquitination involved in ubiquitin-dependent protein catabolic process [IDA]

Gene Ontology Molecular Function

DNA replication origin binding [IPI]
protein binding, bridging [IMP, IPI]
ubiquitin protein ligase activity [IDA]
ubiquitin-protein transferase activity [IDA]

Gene Ontology Cellular Component

SCF ubiquitin ligase complex [IDA, IPI]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

31930

559292

Interactors 536
Interactions 778
Network
PTM Sites 14

Result Summary

CDC53

Gene Ontology Biological Process

Gene Ontology Molecular Function

DNA replication origin binding [IPI]protein binding, bridging [IMP, IPI]ubiquitin protein ligase activity [IDA]ubiquitin-protein transferase activity [IDA]

Gene Ontology Cellular Component

DNA replication origin binding [IPI]
protein binding, bridging [IMP, IPI]
ubiquitin protein ligase activity [IDA]
ubiquitin-protein transferase activity [IDA]