Saccharomyces cerevisiae (S288c)
GPD1
DAR1, HOR1, OSG1, OSR5, glycerol-3-phosphate dehydrogenase (NAD(+)) GPD1, L000000722, YDL022W
NAD-dependent glycerol-3-phosphate dehydrogenase; key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; protein abundance increases in response to DNA replication stress; constitutively inactivated via phosphorylation by the protein kinases YPK1 and YPK2, dephosphorylation increases catalytic activity; GPD1 has a paralog, GPD2, that arose from the whole genome duplication
GO Process (2)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
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- Interactors 161
- Interactions 196
- Network
- PTM Sites 15