Saccharomyces cerevisiae (S288c)
MCD1
PDS3, RHC21, SCC1, L000002676, YDL003W
Essential alpha-kleisin subunit of the cohesin complex; required for sister chromatid cohesion in mitosis and meiosis; apoptosis induces cleavage and translocation of a C-terminal fragment to mitochondria; expression peaks in S phase
GO Process (7)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
- DNA unwinding involved in DNA replication [IMP]
- apoptotic process [IMP]
- cellular response to DNA damage stimulus [IMP]
- double-strand break repair [IMP]
- establishment of mitotic sister chromatid cohesion [IMP]
- mitotic chromosome condensation [IMP]
- replication-born double-strand break repair via sister chromatid exchange [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
32051
559292
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- Interactors 670
- Interactions 1,024
- Network
- PTM Sites 12