Interaction Summary

Gene / Identifier Search

Saccharomyces cerevisiae

DOA4

NPI2, SSV7, MUT4, DOS1, UBP4, YDR069C

Ubiquitin isopeptidase, required for recycling ubiquitin from proteasome-bound ubiquitinated intermediates, acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins en route to the vacuole

GO Process: 7 Terms

GO Function: 3 Terms

GO Component: 4 Terms

Gene Ontology Biological Process

endocytosis [IMP]

free ubiquitin chain depolymerization [IDA]

protein deubiquitination [TAS]

regulation of DNA replication [IMP]

ubiquitin homeostasis [IMP]

ubiquitin-dependent protein catabolic process [IMP]

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [IMP]

Gene Ontology Molecular Function

endopeptidase activity [IGI, IPI]
ubiquitin thiolesterase activity [IDA, IMP]
ubiquitin-specific protease activity [IDA]

Gene Ontology Cellular Component

endosome [IDA]

membrane fraction [IDA]

mitochondrion [IDA]

proteasome complex [IPI]

External Database Linkouts

Download 112 Associations For This Protein

32124

559292

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5 PTM Sites