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Saccharomyces cerevisiae (S288c)

SWI5

DNA-binding transcription factor SWI5, L000002253, YDR146C

Transcription factor that recruits Mediator and Swi/Snf complexes; activates transcription of genes expressed at the M/G1 phase boundary and in G1 phase; required for expression of the HO gene controlling mating type switching; localization to nucleus occurs during G1 and appears to be regulated by phosphorylation by Cdc28p kinase; SWI5 has a paralog, ACE2, that arose from the whole genome duplication

GO Process (3)

GO Function (4)

GO Component (2)

Gene Ontology Biological Process

positive regulation of mating type switching [IMP]

positive regulation of transcription on exit from mitosis, from RNA polymerase II promoter [IMP]

regulation of transcription involved in G1/S transition of mitotic cell cycle [IMP]

Gene Ontology Molecular Function

RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
mediator complex binding [IMP, IPI]
sequence-specific DNA binding [IDA]
sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity [IMP]

Gene Ontology Cellular Component

cytoplasm [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

32200

559292

Interactors 431
Interactions 641
Network
PTM Sites 37