BioGRID COVID-19 Coronavirus Curation Project
Search BioGRID for SARS-CoV-2 Protein Interactions | Download SARS-CoV-2 and Coronavirus-Related Interactions

Saccharomyces cerevisiae (S288c)

REF2

L000002661, YDR195W

RNA-binding protein; involved in the cleavage step of mRNA 3'-end formation prior to polyadenylation, and in snoRNA maturation; part of holo-CPF subcomplex APT, which associates with 3'-ends of snoRNA- and mRNA-encoding genes; relocalizes to the cytosol in response to hypoxia

GO Process (4)

GO Function (2)

GO Component (3)

Gene Ontology Biological Process

mRNA 3'-end processing [IMP]

negative regulation of mRNA polyadenylation [IMP]

snoRNA 3'-end processing [IMP]

termination of RNA polymerase II transcription, poly(A)-coupled [IMP]

Gene Ontology Molecular Function

RNA binding [IDA]
chromatin binding [IDA]

Gene Ontology Cellular Component

mRNA cleavage and polyadenylation specificity factor complex [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

32247

559292

Interactors 305
Interactions 443
Network
PTM Sites 3