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Saccharomyces cerevisiae (S288c)

GIC2

L000003314, YDR309C

Redundant rho-like GTPase Cdc42p effector; involved in initiation of budding and cellular polarization; interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain and with PI(4,5)P2 via a polybasic region; GIC2 has a paralog, GIC1, that arose from the whole genome duplication

GO Process (4)

GO Function (3)

GO Component (4)

Gene Ontology Biological Process

establishment of cell polarity [IGI]

positive regulation of formin-nucleated actin cable assembly [IMP]

regulation of exit from mitosis [IMP, IPI]

septin ring organization [IGI, IPI]

Gene Ontology Molecular Function

Rho GTPase activator activity [IDA, IGI, IPI]
Rho GTPase binding [IPI]
phosphatidylinositol-4,5-bisphosphate binding [IDA, IMP]

Gene Ontology Cellular Component

cellular bud tip [IDA]

incipient cellular bud site [IDA]

mating projection tip [IDA]

plasma membrane [IGI]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

32362

559292

Interactors 132
Interactions 203
Network
PTM Sites 18