Saccharomyces cerevisiae (S288c)
HPT1
BRA6, hypoxanthine phosphoribosyltransferase, HGPRTase, HPRT, L000004313, YDR399W
Dimeric hypoxanthine-guanine phosphoribosyltransferase; catalyzes the transfer of the phosphoribosyl portion of 5-phosphoribosyl-alpha-1-pyrophosphate to a purine base (either guanine or hypoxanthine) to form pyrophosphate and a purine nucleotide (either guanosine monophosphate or inosine monophosphate); mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome
GO Process (2)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- GMP salvage [IDA, IGI, IMP]
- IMP salvage [IDA]
Gene Ontology Molecular Function
Download Curated Data for this Protein
32460
559292
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- Interactors 244
- Interactions 371
- Network
- PTM Sites 4