Saccharomyces cerevisiae (S288c)

ORC2

RRR1, SIR5, origin recognition complex subunit 2, L000001776, YBR060C

Subunit of the origin recognition complex (ORC); ORC directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; interacts with Spp1p and with trimethylated histone H3; phosphorylated by Cdc28p

GO Process (5)

GO Function (2)

GO Component (3)

Gene Ontology Biological Process

DNA replication initiation [IGI, IMP]

chromatin silencing at silent mating-type cassette [IDA]

chromatin silencing at telomere [IMP]

histone H3-K4 methylation [IMP]

pre-replicative complex assembly involved in nuclear cell cycle DNA replication [IDA]

Gene Ontology Molecular Function

DNA replication origin binding [IDA]
chromatin binding [IDA]

Gene Ontology Cellular Component

DNA replication preinitiation complex [IDA]

nuclear origin of replication recognition complex [IDA, IMP]

nuclear pre-replicative complex [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

32764

559292

Interactors 697
Interactions 1,074
Network
PTM Sites 17

Result Summary

ORC2

Gene Ontology Biological Process

Gene Ontology Molecular Function

DNA replication origin binding [IDA]chromatin binding [IDA]

Gene Ontology Cellular Component

DNA replication origin binding [IDA]
chromatin binding [IDA]