Saccharomyces cerevisiae (S288c)

RPL7A

ribosomal 60S subunit protein L7A, YL8, L7A, L6A, L30, rp11, L000002704, L000003255, YGL076C
Ribosomal 60S subunit protein L7A; required for processing of 27SA3 pre-rRNA to 27SB pre-rRNA during assembly of large ribosomal subunit; depletion leads to a turnover of pre-rRNA; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2); binds to Domain II of 25S and 5.8S rRNAs; homologous to mammalian ribosomal protein L7 and bacterial L30; RPL7A has a paralog, RPL7B, that arose from the whole genome duplication
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  • Interactors 268
  • Interactions 310
  • Network
  • PTM Sites 18