Saccharomyces cerevisiae (S288c)

PGD1

HRS1, MED3, L000000811, L000001408, YGL025C

Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for basal and activated transcription; direct target of Cyc8p-Tup1p transcriptional corepressor

GO Process (3)

GO Function (3)

GO Component (1)

Gene Ontology Biological Process

RNA polymerase II transcriptional preinitiation complex assembly [IMP]

negative regulation of transcription from RNA polymerase II promoter [IMP]

positive regulation of transcription from RNA polymerase II promoter [IMP]

Gene Ontology Molecular Function

RNA polymerase II activating transcription factor binding [IDA]
RNA polymerase II repressing transcription factor binding [IPI]
RNA polymerase II transcription factor recruiting transcription factor activity [IMP]

Gene Ontology Cellular Component

core mediator complex [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

33222

559292

Interactors 197
Interactions 318
Network
PTM Sites 1

Result Summary

PGD1

Gene Ontology Biological Process

Gene Ontology Molecular Function

RNA polymerase II activating transcription factor binding [IDA]RNA polymerase II repressing transcription factor binding [IPI]RNA polymerase II transcription factor recruiting transcription factor activity [IMP]

Gene Ontology Cellular Component

RNA polymerase II activating transcription factor binding [IDA]
RNA polymerase II repressing transcription factor binding [IPI]
RNA polymerase II transcription factor recruiting transcription factor activity [IMP]