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Saccharomyces cerevisiae (S288c)

TIF4631

eiF4G1, L000002309, YGR162W

Translation initiation factor eIF4G; subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); interacts with Pab1p and with eIF4A (Tif1p); also has a role in biogenesis of the large ribosomal subunit; TIF4631 has a paralog, TIF4632, that arose from the whole genome duplication

GO Process (3)

GO Function (3)

GO Component (5)

Gene Ontology Biological Process

ribosomal large subunit biogenesis [IMP]

stress granule assembly [IMP]

translational initiation [IMP]

Gene Ontology Molecular Function

RNA binding [IDA]
mRNA binding [IDA]
translation initiation factor activity [TAS]

Gene Ontology Cellular Component

cytoplasm [IDA]

cytoplasmic mRNA processing body [IDA]

cytoplasmic stress granule [IDA]

eukaryotic translation initiation factor 4F complex [IGI, IMP, ISS]

mitochondrion [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

33414

559292

Interactors 457
Interactions 675
Network
PTM Sites 35