Saccharomyces cerevisiae (S288c)

MVB12

ubiquitin-binding ESCRT-I subunit protein MVB12, YGR206W

ESCRT-I subunit required to stabilize ESCRT-I core complex oligomers; the ESCRT-I core complex (Stp22p, Vps28p, Srn2p) is involved in ubiquitin-dependent sorting of proteins into the endosome; deletion mutant is sensitive to rapamycin and nystatin

GO Process (3)

GO Function (1)

GO Component (3)

Gene Ontology Biological Process

endosome transport via multivesicular body sorting pathway [IC]

negative regulation of protein complex assembly [IMP]

protein targeting to vacuole [IMP]

Gene Ontology Molecular Function

ubiquitin binding [IDA]

Gene Ontology Cellular Component

ESCRT I complex [IDA, IPI]

cytosol [IDA]

endosome [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

33459

559292

Interactors 163
Interactions 205
Network
PTM Sites 3

Result Summary

MVB12

Gene Ontology Biological Process

Gene Ontology Molecular Function

ubiquitin binding [IDA]

Gene Ontology Cellular Component