BioGRID COVID-19 Coronavirus Curation Project
Search BioGRID for SARS-CoV-2 Protein Interactions | Download SARS-CoV-2 and Coronavirus-Related Interactions

Saccharomyces cerevisiae (S288c)

NUC1

L000001283, YJL208C

Major mitochondrial nuclease; has RNAse and DNA endo- and exonucleolytic activities; roles in mitochondrial recombination, apoptosis and maintenance of polyploidy; involved in fragmentation of genomic DNA during PND (programmed nuclear destruction); encodes ortholog of mammalian endoG

GO Process (5)

GO Function (3)

GO Component (3)

Gene Ontology Biological Process

DNA catabolic process [IDA]

DNA recombination [IMP]

RNA catabolic process [IDA]

apoptotic DNA fragmentation [IMP]

apoptotic process [IMP]

Gene Ontology Molecular Function

endodeoxyribonuclease activity [IDA]
exodeoxyribonuclease activity [IDA]
ribonuclease activity [IDA]

Gene Ontology Cellular Component

mitochondrial inner membrane [IDA]

mitochondrion [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

33550

559292

Interactors 152
Interactions 195
Network
PTM Sites 1