Saccharomyces cerevisiae (S288c)

PHS1

enoyl-CoA hydratase PHS1, YJL097W

Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane; involved in elongation of very long-chain fatty acids; evolutionarily conserved, similar to mammalian PTPLA and PTPLB; involved in sphingolipid biosynthesis and protein trafficking

GO Process (3)

GO Function (2)

GO Component (6)

Gene Ontology Biological Process

fatty acid elongation [IMP]

sphingolipid biosynthetic process [IMP]

vacuolar transport [IMP]

Gene Ontology Molecular Function

3-hydroxyacyl-CoA dehydratase activity [IMP]
enoyl-CoA hydratase activity [IDA]

Gene Ontology Cellular Component

endoplasmic reticulum [IDA]

fungal-type vacuole [IDA]

fungal-type vacuole membrane [IDA]

integral component of endoplasmic reticulum membrane [IDA]

integral component of membrane [ISM]

nuclear outer membrane-endoplasmic reticulum membrane network [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

33660

559292

Interactors 284
Interactions 309
Network

Result Summary

PHS1

Gene Ontology Biological Process

Gene Ontology Molecular Function

3-hydroxyacyl-CoA dehydratase activity [IMP]enoyl-CoA hydratase activity [IDA]

Gene Ontology Cellular Component

3-hydroxyacyl-CoA dehydratase activity [IMP]
enoyl-CoA hydratase activity [IDA]