Saccharomyces cerevisiae (S288c)

TRL1

LIG1, RLG1, tRNA ligase, L000002336, YJL087C

tRNA ligase; required for tRNA splicing and for both splicing and translation of HAC1 mRNA in the UPR; has phosphodiesterase, polynucleotide kinase, and ligase activities; localized at the inner nuclear envelope and partially to polysomes

GO Process (3)

GO Function (3)

GO Component (2)

Gene Ontology Biological Process

UFP-specific transcription factor mRNA processing involved in endoplasmic reticulum unfolded protein response [IMP]

positive regulation of translation in response to stress [IMP, IPI]

tRNA splicing, via endonucleolytic cleavage and ligation [IDA, IMP]

Gene Ontology Molecular Function

2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [IDA]
GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity [IDA]
RNA ligase (ATP) activity [IDA]

Gene Ontology Cellular Component

nuclear inner membrane [IDA]

polysome [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

33670

559292

Interactors 20
Interactions 22
Network

Result Summary

TRL1

Gene Ontology Biological Process

Gene Ontology Molecular Function

2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [IDA]GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity [IDA]RNA ligase (ATP) activity [IDA]

Gene Ontology Cellular Component

2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [IDA]
GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity [IDA]
RNA ligase (ATP) activity [IDA]