Interaction Summary

Gene / Identifier Search

Saccharomyces cerevisiae

KAR2

GRP78, YJL034W

ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p

GO Process: 5 Terms

GO Function: 2 Terms

GO Component: 2 Terms

Gene Ontology Biological Process

ER-associated protein catabolic process [IMP]

SRP-dependent cotranslational protein targeting to membrane, translocation [IMP]

karyogamy involved in conjugation with cellular fusion [IGI, IMP]

posttranslational protein targeting to membrane, translocation [IDA, IMP]

response to unfolded protein [IMP]

Gene Ontology Molecular Function

ATPase activity [IDA]
unfolded protein binding [IMP]

Gene Ontology Cellular Component

endoplasmic reticulum [IDA]

luminal surveillance complex [IDA]

External Database Linkouts

Download 440 Associations For This Protein

33726

559292

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5 PTM Sites