Saccharomyces cerevisiae (S288c)

HIR3

HPC1, L000003127, YJR140C

Subunit of the HIR complex; a nucleosome assembly complex involved in regulation of histone gene transcription; involved in position-dependent gene silencing and nucleosome reassembly; ortholog of human CABIN1 protein

GO Process (4)

GO Function (3)

GO Component (2)

Gene Ontology Biological Process

DNA replication-independent nucleosome assembly [IDA]

negative regulation of transcription involved in G1/S transition of mitotic cell cycle [IMP]

positive regulation of histone acetylation [IMP]

transcription elongation from RNA polymerase II promoter [IGI]

Gene Ontology Molecular Function

DNA binding [IDA]
nucleosome binding [IMP]
transcription corepressor activity [IMP]

Gene Ontology Cellular Component

HIR complex [IDA, IPI]

nucleus [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

33896

559292

Interactors 367
Interactions 617
Network
PTM Sites 3

Result Summary

HIR3

Gene Ontology Biological Process

Gene Ontology Molecular Function

DNA binding [IDA]nucleosome binding [IMP]transcription corepressor activity [IMP]

Gene Ontology Cellular Component

DNA binding [IDA]
nucleosome binding [IMP]
transcription corepressor activity [IMP]