Saccharomyces cerevisiae (S288c)

SNU114

GIN10, U5 snRNP GTPase SNU114, L000003541, YKL173W

GTPase component of U5 snRNP involved in mRNA splicing via spliceosome; binds directly to U5 snRNA; proposed to be involved in conformational changes of the spliceosome; similarity to ribosomal translocation factor EF-2

GO Process (4)

GO Function (2)

GO Component (2)

Gene Ontology Biological Process

generation of catalytic spliceosome for first transesterification step [IGI]

mRNA splicing, via spliceosome [IMP]

spliceosomal tri-snRNP complex assembly [IMP]

spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) [IMP]

Gene Ontology Molecular Function

GTPase activity [IMP]
U5 snRNA binding [IDA]

Gene Ontology Cellular Component

U4/U6 x U5 tri-snRNP complex [IDA]

U5 snRNP [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

33965

559292

Interactors 445
Interactions 727
Network
PTM Sites 4

Result Summary

SNU114

Gene Ontology Biological Process

Gene Ontology Molecular Function

GTPase activity [IMP]U5 snRNA binding [IDA]

Gene Ontology Cellular Component

GTPase activity [IMP]
U5 snRNA binding [IDA]