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Saccharomyces cerevisiae (S288c)

RPT1

CIM5, YTA3, proteasome regulatory particle base subunit RPT1, L000002557, YKL145W

ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; required for optimal CDC20 transcription; interacts with Rpn12p and Ubr1p; mutant has aneuploidy tolerance

GO Process (4)

GO Function (1)

GO Component (1)

Gene Ontology Biological Process

positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [IMP]

positive regulation of protein catabolic process [IDA]

proteasome regulatory particle assembly [IMP]

ubiquitin-dependent protein catabolic process [IPI]

Gene Ontology Molecular Function

ATPase activity [ISS]

Gene Ontology Cellular Component

proteasome regulatory particle, base subcomplex [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

33991

559292

Interactors 674
Interactions 1,188
Network
PTM Sites 33