Saccharomyces cerevisiae (S288c)
MPE1
YKL059C
Essential conserved subunit of CPF cleavage and polyadenylation factor; plays a role in 3' end formation of mRNA via the specific cleavage and polyadenylation of pre-mRNA; contains a ubiquitin-like (UBL) domain, a RNA-binding zinc knuckle motif and a RING finger domain; both the zinc knuckle and RING finger are required for pre-mRNA binding; possible role in ubiquitination of Pap1p; relocalizes to the cytosol in response to hypoxia
GO Process (3)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
- mRNA cleavage [IDA, IGI, IMP, IPI]
- mRNA polyadenylation [IDA, IGI, IMP, IPI]
- protein ubiquitination [IGI, IMP]
Gene Ontology Molecular Function
Download Curated Data for this Protein
34074
559292
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- Interactors 245
- Interactions 375
- Network
- PTM Sites 2