Saccharomyces cerevisiae (S288c)

IXR1

ORD1, L000000881, YKL032C
Transcriptional repressor that regulates hypoxic genes during normoxia; involved in the aerobic repression of genes such as COX5b, TIR1, and HEM13; binds DNA intrastrand cross-links formed by cisplatin; HMG (high mobility group box) domain containing protein which binds and bends cisplatin-modified DNA, blocking excision repair; IXR1 has a paralog, ABF2, that arose from the whole genome duplication
PHO
SUMO
GO Process (3)
GO Function (2)
GO Component (1)

External Database Linkouts

SGD | Entrez Gene | RefSeq | UniprotKB | PhosphoGRID
Download 266 Published Interactions For This Protein
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  • Interactors (223)
  • Interactions (266)
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  • PTM Sites (3)