Saccharomyces cerevisiae (S288c)

HRD1

DER3, E3 ubiquitin-protein ligase HRD1, L000002963, YOL013C
Ubiquitin-protein ligase; functions in ER retention of misfolded proteins; required for ER-associated degradation (ERAD) of misfolded proteins; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger; likely plays a general role in targeting proteins that persistently associate with and potentially obstruct the ER-localized translocon
Download Curated Data for this Protein
34391
559292
Switch View:
  • Interactors 182
  • Interactions 402
  • Network
  • PTM Sites 4