Saccharomyces cerevisiae (S288c)
HRD1
DER3, E3 ubiquitin-protein ligase HRD1, L000002963, YOL013C
Ubiquitin-protein ligase; functions in ER retention of misfolded proteins; required for ER-associated degradation (ERAD) of misfolded proteins; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger; likely plays a general role in targeting proteins that persistently associate with and potentially obstruct the ER-localized translocon
GO Process (4)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
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34391
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- Interactors 182
- Interactions 402
- Network
- PTM Sites 4