Saccharomyces cerevisiae (S288c)


MAK1, MAK17, DNA topoisomerase 1, L000002319, YOL006C
Topoisomerase I; nuclear enzyme that relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone; relaxes both positively and negatively supercoiled DNA; functions in replication, transcription, and recombination; role in processing ribonucleoside monophosphates in genomic DNA into irreversible single-strand breaks

External Database Linkouts

SGD | Entrez Gene | RefSeq | UniprotKB | PhosphoGRID
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  • PTM Sites (9)