BioGRID COVID-19 Coronavirus Curation Project
Search BioGRID for SARS-CoV-2 Protein Interactions | Download SARS-CoV-2 and Coronavirus-Related Interactions

Saccharomyces cerevisiae (S288c)

SKI7

YOR29-27, YOR076C

Coupling protein for the Ski complex and cytoplasmic exosome; involved in 3'-5' RNA degradation; eRF3-like domain targets nonstop mRNA for degradation; null mutants have superkiller phenotype; SKI7 has a paralog, HBS1, that arose from the whole genome duplication

GO Process (4)

GO Function (1)

GO Component (3)

Gene Ontology Biological Process

nonfunctional rRNA decay [IMP]

nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [IGI, IMP]

nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [IGI, IMP]

nuclear-transcribed mRNA catabolic process, non-stop decay [IMP]

Gene Ontology Molecular Function

protein binding, bridging [IMP]

Gene Ontology Cellular Component

Ski complex [IDA]

cytoplasm [IDA]

cytoplasmic exosome (RNase complex) [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

34475

559292

Interactors 174
Interactions 345
Network
PTM Sites 3