Saccharomyces cerevisiae (S288c)

PNO1

DIM2, RRP20, YOR145C

Essential nucleolar protein required for pre-18S rRNA processing; interacts with Dim1p, an 18S rRNA dimethyltransferase, and also with Nob1p, which is involved in proteasome biogenesis; contains a KH domain

GO Process (3)

GO Function (1)

GO Component (3)

Gene Ontology Biological Process

endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [IMP]

endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [IMP]

protein complex assembly [IMP, IPI]

Gene Ontology Molecular Function

unfolded protein binding [IDA, IPI]

Gene Ontology Cellular Component

90S preribosome [IDA]

nucleolus [IDA]

nucleus [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

34542

559292

Interactors 155
Interactions 235
Network
PTM Sites 6

Result Summary

PNO1

Gene Ontology Biological Process

Gene Ontology Molecular Function

unfolded protein binding [IDA, IPI]

Gene Ontology Cellular Component