Saccharomyces cerevisiae (S288c)
LAS17
BEE1, L000003068, L000003581, YOR181W
Actin assembly factor; C-terminal WCA domain activates Arp2/3 complex-mediated nucleation of branched actin filaments and a polyproline domain which can nucleate actin filaments independent of Arp2/3; mutants are defective in actin cytoskeleton dependent processes such as: endocytosis, bud site selection and cytokinesis; localizes with the Arp2/3 complex to actin cortical patches; homolog of the Wiskott-Aldrich Syndrome protein (WASP), implicated in severe immunodeficiency
GO Process (6)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function- actin binding [IDA, IPI]
- actin binding [IDA, IPI]
Gene Ontology Cellular Component
Download Curated Data for this Protein
34576
559292
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- Interactors 750
- Interactions 1,096
- Network
- PTM Sites 7