Saccharomyces cerevisiae (S288c)

SEC63

PTL1, protein-transporting protein SEC63, L000001854, L000001269, YOR254C

Essential subunit of Sec63 complex; with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER; other members are Sec62p, Sec66p, and Sec72p

GO Process (4)

GO Function (1)

GO Component (4)

Gene Ontology Biological Process

SRP-dependent cotranslational protein targeting to membrane [IMP]

cytosol to ER transport [IMP]

posttranslational protein targeting to membrane [IMP]

posttranslational protein targeting to membrane, translocation [IDA]

Gene Ontology Molecular Function

protein transporter activity [IMP]

Gene Ontology Cellular Component

Sec62/Sec63 complex [IPI]

endoplasmic reticulum membrane [TAS]

integral component of membrane [ISM]

mitochondrion [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

34644

559292

Interactors 676
Interactions 1,077
Network
PTM Sites 8

Result Summary

SEC63

Gene Ontology Biological Process

Gene Ontology Molecular Function

protein transporter activity [IMP]

Gene Ontology Cellular Component