Saccharomyces cerevisiae (S288c)
GPB1
KRH2, YOR371C
Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; promotes ubiquitin-dependent proteolysis of Ira2p; regulated by G-alpha protein Gpa2p; GPB1 has a paralog, GPB2, that arose from the whole genome duplication
GO Process (9)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
- glucose mediated signaling pathway [IGI, IMP]
- invasive growth in response to glucose limitation [IGI, IMP]
- negative regulation of Ras protein signal transduction [IGI]
- negative regulation of phosphorylation [IGI]
- positive regulation of Ras protein signal transduction [IMP]
- protein polyubiquitination [IDA]
- protein ubiquitination involved in ubiquitin-dependent protein catabolic process [IDA, IMP]
- pseudohyphal growth [IGI, IMP]
- signal transduction [IPI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
34754
559292
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- Interactors 57
- Interactions 77
- Network
- PTM Sites 9