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Saccharomyces cerevisiae (S288c)

POB3

FACT complex subunit POB3, L000003326, YML069W

Subunit of the heterodimeric FACT complex (Spt16p-Pob3p); FACT associates with chromatin via interaction with Nhp6Ap and Nhp6Bp, and reorganizes nucleosomes to facilitate access to DNA by RNA and DNA polymerases; protein abundance increases in response to DNA replication stress

GO Process (4)

GO Function (3)

GO Component (4)

Gene Ontology Biological Process

DNA replication-independent nucleosome organization [IDA]

DNA-dependent DNA replication [IGI, IMP, IPI]

chromatin organization involved in regulation of transcription [IC]

positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [IDA]

Gene Ontology Molecular Function

chromatin binding [IDA]
histone binding [IDA]
nucleosome binding [IDA]

Gene Ontology Cellular Component

FACT complex [IDA, IGI, IPI]

alpha DNA polymerase:primase complex [IDA]

nuclear chromatin [IDA]

replication fork protection complex [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

35097

559292

Interactors 744
Interactions 1,179
Network
PTM Sites 13