Saccharomyces cerevisiae (S288c)

PEP5

END1, VAM1, VPL9, VPS11, VPT11, tethering complex subunit PEP5, L000001376, L000002957, YMR231W

Histone E3 ligase, component of CORVET membrane tethering complex; peripheral vacuolar membrane protein required for protein trafficking and vacuole biogenesis; interacts with Pep7p; involved in ubiquitylation and degradation of excess histones

UPS Project

GO Process (7)

GO Function (2)

GO Component (3)

Gene Ontology Biological Process

Golgi to endosome transport [IGI]

histone catabolic process [IMP]

histone ubiquitination [IDA]

late endosome to vacuole transport [IGI]

regulation of SNARE complex assembly [IDA]

regulation of vacuole fusion, non-autophagic [IDA]

vacuole fusion, non-autophagic [IDA, IMP]

Gene Ontology Molecular Function

phosphatidylinositol binding [IDA]
ubiquitin-protein transferase activity [IDA]

Gene Ontology Cellular Component

CORVET complex [IDA]

HOPS complex [IPI]

fungal-type vacuole membrane [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

35409

559292

Interactors 96
Interactions 218
Network
PTM Sites 3

Result Summary

PEP5

Gene Ontology Biological Process

Gene Ontology Molecular Function

phosphatidylinositol binding [IDA]ubiquitin-protein transferase activity [IDA]

Gene Ontology Cellular Component

phosphatidylinositol binding [IDA]
ubiquitin-protein transferase activity [IDA]