Saccharomyces cerevisiae (S288c)


GYP3, L000003918, YNL293W
Rab GTPase-activating protein; regulates endocytosis via inactivation of Vps21p at endosomes and vacuole fusion via inactivation of Ypt7p at vacuoles; also acts on Ypt52p and Sec4p; required for proper actin organization; also localizes to plasma membrane and sites of polarized growth; relocalizes from bud neck to cytoplasm upon DNA replication stress; similar to the TBC-domain Tre2 oncogene; MSB3 has a paralog, MSB4, that arose from the whole genome duplication

External Database Linkouts

SGD | Entrez Gene | RefSeq | UniprotKB | PhosphoGRID
Download 92 Published Interactions For This Protein
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  • Interactors (67)
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  • PTM Sites (6)