Saccharomyces cerevisiae (S288c)
APC1
anaphase promoting complex subunit 1, L000004053, YNL172W
Largest subunit of the Anaphase-Promoting Complex/Cyclosome; APC/C is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; component of the platform domain of the APC/C, based on structural analysis; localizes to nuclear foci that become diffuse upon DNA replication stress
GO Process (5)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process [IMP]
- exit from mitosis [IMP]
- metaphase/anaphase transition of mitotic cell cycle [IMP]
- negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation [IMP]
- protein ubiquitination [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
35658
559292
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- Interactors 513
- Interactions 610
- Network
- PTM Sites 6