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Saccharomyces cerevisiae (S288c)

INP52

SJL2, phosphatidylinositol-3-/phosphoinositide 5-phosphatase INP52, L000003985, YNL106C

Polyphosphatidylinositol phosphatase; dephosphorylates a number of phosphatidylinositol phosphates (PtdInsPs, PIPs) to PI; involved in endocytosis; hyperosmotic stress causes translocation to actin patches; synaptojanin-like protein with a Sac1 domain; INP52 has a paralog, INP53, that arose from the whole genome duplication

GO Process (1)

GO Function (4)

GO Component (3)

Gene Ontology Biological Process

phosphatidylinositol dephosphorylation [IDA, IMP]

Gene Ontology Molecular Function

phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity [IDA]
phosphatidylinositol-3-phosphatase activity [IDA]
phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [IDA, IMP]
phosphatidylinositol-4-phosphate phosphatase activity [IDA]

Gene Ontology Cellular Component

actin cortical patch [IDA, IPI]

cytoplasm [IDA]

mating projection tip [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

35718

559292

Interactors 204
Interactions 277
Network
PTM Sites 18