Saccharomyces cerevisiae (S288c)

PMS1

L000001457, YNL082W

ATP-binding protein required for mismatch repair; required for both mitosis and meiosis; functions as a heterodimer with Mlh1p; binds double- and single-stranded DNA via its N-terminal domain, similar to E. coli MutL

GO Process (3)

GO Function (7)

GO Component (3)

Gene Ontology Biological Process

meiotic mismatch repair [IMP]

mismatch repair [IMP]

reciprocal meiotic recombination [IBA]

Gene Ontology Molecular Function

ATP binding [IMP]
ATPase activity [IDA, IMP]
DNA insertion or deletion binding [IDA]
dinucleotide insertion or deletion binding [IDA]
double-stranded DNA binding [IDA]
heteroduplex DNA loop binding [IDA]
single-stranded DNA binding [IDA]

Gene Ontology Cellular Component

MutLalpha complex [IPI]

cytoplasm [IDA]

nucleus [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

35741

559292

Interactors 250
Interactions 355
Network
PTM Sites 8

Result Summary

PMS1

Gene Ontology Biological Process

Gene Ontology Molecular Function

ATP binding [IMP]ATPase activity [IDA, IMP]DNA insertion or deletion binding [IDA]dinucleotide insertion or deletion binding [IDA]double-stranded DNA binding [IDA]heteroduplex DNA loop binding [IDA]single-stranded DNA binding [IDA]

Gene Ontology Cellular Component

ATP binding [IMP]
ATPase activity [IDA, IMP]
DNA insertion or deletion binding [IDA]
dinucleotide insertion or deletion binding [IDA]
double-stranded DNA binding [IDA]
heteroduplex DNA loop binding [IDA]
single-stranded DNA binding [IDA]