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Saccharomyces cerevisiae (S288c)

SPP1

CPS40, SAF41, YPL138C

Subunit of COMPASS (Set1C); a complex which methylates histone H3 on lysine 4 and is required in telomeric transcriptional silencing; interacts with Orc2p; PHD finger domain protein similar to human CGBP, an unmethylated CpG binding protein; relocalizes to the cytosol in response to hypoxia

GO Process (3)

GO Function (3)

GO Component (3)

Gene Ontology Biological Process

chromatin silencing at telomere [IMP]

histone H3-K4 methylation [IDA, IMP]

regulation of transcription, DNA-templated [IMP]

Gene Ontology Molecular Function

chromatin binding [IDA]
histone methyltransferase activity (H3-K4 specific) [IDA, IMP]
methylated histone binding [IDA]

Gene Ontology Cellular Component

Set1C/COMPASS complex [IPI]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

36044

559292

Interactors 170
Interactions 311
Network
PTM Sites 1