Saccharomyces cerevisiae (S288c)


SPP42, L000000612, YPR104C
Regulator of ribosomal protein (RP) transcription; has forkhead associated domain that binds phosphorylated proteins; recruits coactivator Ifh1p or corepressor Crf1p to RP gene promoters; also has forkhead DNA-binding domain though in vitro DNA binding assays give inconsistent results; computational analyses suggest it binds DNA directly at highly active RP genes and indirectly through Rap1p motifs at others; suppresses RNA pol III and splicing factor prp4 mutants

External Database Linkouts

SGD | Entrez Gene | RefSeq | UniprotKB | PhosphoGRID
Download 55 Published Interactions For This Protein
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  • Interactors (43)
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  • PTM Sites (10)