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Saccharomyces cerevisiae (S288c)

SCD6

LSM13, L000001806, YPR129W

Repressor of translation initiation; binds eIF4G through its RGG domain and inhibits recruitment of the preinitiation complex; also contains an Lsm domain; may have a role in RNA processing; overproduction suppresses null mutation in clathrin heavy chain gene CHC1; forms cytoplasmic foci upon DNA replication stress

GO Process (3)

GO Function (3)

GO Component (3)

Gene Ontology Biological Process

cytoplasmic mRNA processing body assembly [IMP]

negative regulation of translational initiation [IDA, IMP]

stress granule assembly [IMP]

Gene Ontology Molecular Function

RNA binding [ISS]
eukaryotic initiation factor 4G binding [IDA]
mRNA binding [IDA]

Gene Ontology Cellular Component

cytoplasm [IDA]

cytoplasmic mRNA processing body [IDA]

cytoplasmic stress granule [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

36296

559292

Interactors 202
Interactions 264
Network
PTM Sites 2