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Saccharomyces cerevisiae (S288c)

SPN1

IWS1, YPR133C

Protein involved in RNA polymerase II transcription; is constitutively recruited to the CYC1 promoter and is required for recruitment of chromatin remodeling factors for the expression of CYC1 gene; interacts genetically or physically with RNAP II, TBP, TFIIS, and chromatin remodelling factors; central domain highly conserved throughout eukaryotes; mutations confer an Spt- phenotype

GO Process (4)

GO Function (2)

GO Component (1)

Gene Ontology Biological Process

chromatin organization involved in regulation of transcription [IMP, IPI]

poly(A)+ mRNA export from nucleus [IMP]

regulation of transcription elongation from RNA polymerase II promoter [IGI]

regulation of transcription from RNA polymerase II promoter [IGI, IPI]

Gene Ontology Molecular Function

RNA polymerase II transcription factor binding transcription factor activity [IPI]
core RNA polymerase II binding transcription factor activity [IPI]

Gene Ontology Cellular Component

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

36299

559292

Interactors 476
Interactions 680
Network
PTM Sites 23