Saccharomyces cerevisiae (S288c)

VPS4

CSC1, DID6, END13, GRD13, VPL4, VPT10, AAA family ATPase VPS4, L000002956, YPR173C

AAA-ATPase involved in multivesicular body (MVB) protein sorting; ATP-bound Vps4p localizes to endosomes and catalyzes ESCRT-III disassembly and membrane release; ATPase activity is activated by Vta1p; regulates cellular sterol metabolism

GO Process (6)

GO Function (3)

GO Component (4)

Gene Ontology Biological Process

intralumenal vesicle formation [IMP]

late endosome to vacuole transport [IMP, IPI]

late endosome to vacuole transport via multivesicular body sorting pathway [IMP]

protein homooligomerization [IDA]

protein retention in Golgi apparatus [IMP]

sterol metabolic process [IGI, IMP]

Gene Ontology Molecular Function

ATP binding [IDA, IMP]
ATPase activity [IDA, IMP]
protein homodimerization activity [IDA]

Gene Ontology Cellular Component

cytoplasm [IDA]

endoplasmic reticulum [IDA]

endosome [IDA]

membrane [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

36346

559292

Interactors 681
Interactions 1,086
Network
PTM Sites 4

Result Summary

VPS4

Gene Ontology Biological Process

Gene Ontology Molecular Function

ATP binding [IDA, IMP]ATPase activity [IDA, IMP]protein homodimerization activity [IDA]

Gene Ontology Cellular Component

ATP binding [IDA, IMP]
ATPase activity [IDA, IMP]
protein homodimerization activity [IDA]